LAB MEMBERS

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PROFESSOR PETER ROY, PHD

Principal Investigator

Peter's lab exploits the nematode C. elegans and other organisms to discover new candidate drugs and new drug targets. In doing so, his group makes important discoveries about the biological roles of targeted proteins. His group focuses on combating parasitic nematodes and other infectious diseases. The Roy Lab also develops new animal models of human disease. Peter's group uses forward genetics, chemical-genetics, next-generation sequencing, molecular biology, analytical chemistry, and pharmacology approaches in their studies. Peter prefers he/him pronouns.

Peter's lab is located in the beautiful Donnelly Centre glass tower, and is a member of the Department of Molecular Genetics, the Department of Pharmacology and Toxicology, UofT's precision medicine initiative PRIME, and the infectious disease consortium EPIC.

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ANDREW BURNS, PHD

Research Associate

Andrew earned his BSc in Biochemistry from Queen’s University and a Ph.D. in Molecular Genetics from the University of Toronto. In the Roy Lab, Andrew has made several pioneering discoveries on small molecule metabolism in nematodes and consequently has several patent applications to his name. He is currently focused on understanding the mechanism of action and utility of his newest discovery, Selectivin™.

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AANCHAL AGGARWAL, MSC

Lab Manager

Aanchal earned her MSc from the University of Saskatchewan and was recruited to the team to keep our ship sailing smoothly. We are so happy to have you on board!!!

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SEAN HARRINGTON, PHD

Post-Doctoral Fellow

Sean received his B.Sc. degree from the University of Guelph and recently completed his PhD at the University of Toronto where he pioneered a novel drug discovery pipeline that yielded Nementin™, a novel nematicide that agonizes dense core vesicle release. Sean has several patents pending from his work in the Roy Lab and is currently working on the development of novel anthelmintic molecules.

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JESS KNOX, MSC

PhD Student (Molecular Genetics)

Jess received her BSc and MSc from MacMaster University. Jess has been a prolific contributor to many Roy Lab projects. In her own work, she has pioneered the culture of nematode parasites in the Roy lab and exploits these cultures to better understand the mechanism of action of a novel nematicide that she discovered.

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MUNTASIR KAMAL, MSC

PhD Student (Molecular Genetics)

Muntasir obtained his BSc from the University of Toronto and an MSc from York University. Muntasir has made numerous discoveries that led to the development of a new animal model of liver disease and a platform to identify new small molecule that disrupt amyloid formation.

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LEVON TOKMAKJIAN, BSC

PhD Student (Dept of Pharm & Tox)

Levon received his BSc from the University of Toronto. He is working to uncover the mechanism by which drugs can suppress the phenotypes of our model of PFIC3 liver disease.

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SYLVIA OKAFOR, BSC

Graduate Student

Sylvia earned her BSc from Delaware State University.  She is co-mentored with Peter and Amy Ramsey from the Dept of Pharmacology and Toxicology. Sylvia is working to develop animal models of NMDA-related GRIN disorders and loves to build new stuff in the lab!

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BRITTANY COOKE, BSC

Graduate Student (Molecular Genetics)

Brittany, who obtained her BSc from Queens University, is the lab's newest graduate student. Brittany is working on the development of a new functional genomics-based drug discovery pipeline targeting multiple human infectious diseases.

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SAVINA CAMMALLERI

Undergraduate Student 2020-2021, 4th year Thesis Project Student, 2022-2023 (Molecular Genetics)

Savina is a talented undergraduate student who has already published a first-author paper (see pubs page). Savina's work is focused on understanding the mechanism of several of our candidate nematicides.

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YUETING (LINDA) REN

4th Year Thesis Project Student (Pharm Tox), 2022-2023

Linda is working to better understand the xenobiotic response network of nematodes.

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OUR WONDERFUL ALUMNI

Circa 2022

Roy Lab alumni are listed below.

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JINGXIU JI

4th Year Thesis Student (Molecular Genetics), 2021-2022

Jingxiu focused on better understanding the construction of the nematode cuticle and was a contributing author on our spatiotemporal reconstruction of the C. elegans pharynx cuticle.

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ZARRIN MOON, BSC

Technical Assistance until 2022

Zarrin was a long long time and valued media tech in the Roy Lab. She has moved on to become a Clinical Imaging Technician in the GTA.  Congrats Zarrin!